Colonel Jacob Duché (1708–1788) was a mayor of Philadelphia in the colonial province of Pennsylvania. Duché was born in Philadelphia, the son of Anthony Duché (d. 1762), a French Huguenot who came with his wife to America in the same ship as William Penn in about 1700. He was appointed a colonel of the militia. He served as mayor of Philadelphia from 1761 to 1762.

He was for many years a vestryman of Christ Church; when the congregation grew too large to be accommodated there, he headed the committee that oversaw the erection of its daughter church, St. Peter's. St. Peter's Church is a historic church located on the corner of Third and Pine Streets in Philadelphia, Pennsylvania. It opened for worship on September 4, 1761 and served as a place of worship for many of the United States Founding Fathers during the period of the Continental Congresses. The building was designated a National Historic Landmark in 1996.

Sources:

• http://en.wikipedia.org/wiki/Jacob_Duch%C3%A9,_Sr.
• http://en.wikipedia.org/wiki/St._Peter%27s_Church,_Philadelphia