George Sandys, who served as Jamestown's inaugural resident treasurer from 1621-25, sold his 400 northside acres in James City to Edward Grendon in the 1620s. When Grendon passed away in 1628, he left the land to his son Thomas, an English merchant. 

Sources:

• http://books.google.com/books?id=orDbMGpInaQC&pg=PA344&lpg=PA344&dq=Edward+Grendon+Jamestown,+Va&source=bl&ots=WHYb5hr3WK&sig=-S57L4NoLhRVuAMpSlKMFPcAxTg&hl=en&sa=X&ei=L5UGUbbbEOS80QG-u4GICQ&ved=0CEAQ6AEwAw#v=onepage&q=Edward%20Grendon%20Jamestown%2C%20Va&f=false
• http://apva.org/rediscovery/page.php?page_id=440