Valerie Hobson, the English actress, appeared as Baroness Frankenstein in Bride of Frankenstein (1935) with Boris Karloff and Colin Clive, taking over the role from Mae Clarke, who had played it in the original Frankenstein (1931). Hobson also played opposite Henry Hull that same year in Werewolf of London, the first Hollywood werewolf film, predating The Wolf Man by six years. The latter half of the 1940s saw Hobson in perhaps her two most memorable roles: as the adult Estella in David Lean's 1946 adaptation of Great Expectations, and as the refined and virtuous Edith D'Ascoyne in the 1949 black comedy Kind Hearts and Coronets. In 1952 she divorced her first husband, film producer Sir Anthony Havelock-Allan (1904–2003), and married MP John Profumo (1915–2006) in 1954, giving up acting shortly afterwards.