The William Edwards who married Grissell Coleman in 1750 Cumberland Co., VA. is not the same one as William Edwards 1720-1801.
William Edwards is listed in the 1782 Cumberland Co., VA tax list. In 1784 Grissel Edwards is listed as Head of Household, and at the Jan 1786 Cumberland Co., VA court the Estate Inventory was entered for William Edwards deceased.
Grizzle Edwards was still alive in December 1827 when a Cumberland Co., VA Chancery court oversaw the land and personal estate of her son William Edwards 1758-1803 deceased, as his mother had been appointed administratrix of his estate, had taken over raising his orphaned children, and never completed the administration of his estate.
Assuming she was 18 years old when she married William Edwards in 1750 Cumberland Co., VA, then in 1827 she was 95 years of age. The residual of William Edwards 1758-1803’s children migrated to Logan County, KY. in the early 1830’s, so Grizzle Edwards had most likely died in the interim.
See: https://sites.rootsweb.com/~theduffypapers/edwards/1720_william_edw...
And
See: https://www.wikitree.com/wiki/Coleman-2415