The current middle name of "Comer" could be indicative that this woman is daughter of John Comer:
Court Order Books, Caroline Co., VA, 14 Feb. 1771. Thomas Comer, Jeremiah Stone and wife Susanna, and William Williams and wife Eliza, v. Annis, John, Charles and Mary, minor children of John Comer, suit to settle the estate of John Comer.