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Son of James Harvey Duff-McDuffee and Nancy Ann Whitson Brother of John Calvin McDuffee; Elizabeth Whitson-Hildebrand-McDuffee; Martha McDuffee; Mary McDuffee; Charles McDuffee and 3 others; Sarah Jane McDuffee; Charlotte )Lottie) McDuffee and Ephriam Hall McDuffee « less Half brother of George Washington Duff; John Carson Duff; Hillard Harris Duff; William L. Duff and Nancy Adeline Duff