James Madison, 4th President of the United States is George Washington, 1st President of the USA's nephew's wife's sister's husband!

George Washington, 1st President of the USA
 

Col. Samuel Washington
his brother

George Steptoe Washington,
his son

Mary Coles Washington
his wife

Dolly Madison, First Lady of the USA
her sister

James Madison, 4th President of the United States
her husband

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