Frances Ford Seymour (April 4, 1908 – 14 April 1950) was a New York City socialite, perhaps most famous as the second wife of actor Henry Fonda and the mother of actors Jane Fonda and Peter Fonda. She suffered from mental illness and committed suicide by cutting her throat with a razor in 1950 while in a sanatorium. She was 42.

Born in Brockville, Ontario, Canada, she was the daughter of Eugene Ford Seymour and Sophie Mildred Bower (Ontario, July 13, 1886 – Los Angeles, California, April 15, 1974). On January 10, 1931 she married George Tuttle Brokaw, a millionaire and prominent New York City socialite whose previous marriage, to Clare Booth Luce, had ended in divorce. They had one child together, Frances Brokaw. George Tuttle Brokaw died in 1936, leaving Frances Ford Seymour widowed at the age of 28.

That year, Frances Ford Seymour was remarried on 16 September 1936 to actor Henry Fonda, at Christ Church in New York City. The couple had two children, Jane Seymour Fonda, and Peter Fonda.