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Son of William Cavendish, 1st Duke of Newcastle-upon-Tyne and Elizabeth Cavendish Howard, Duchess of Newcastle Brother of Lady Jane Cavendish; Charles Cavendish, Viscount Mansfield; Elizabeth Egerton; Henry Cavendish, 2nd Duke of Newcastle-upon-Tyne; William Cavendish and 3 others; Catherine Cavendish; Frances Cavendish and Margaret Cavendish « less Half brother of Katherine or Elizabeth Harpur and Catharine Howard