Lady Mary Wortley Montagu (Pierrepoint)

http://en.wikipedia.org/wiki/Lady_Mary_Wortley_Montagu

Lady Mary Wortley Montagu (15 May 1689 – 21 August 1762) was an English aristocrat and writer. Montagu is today chiefly remembered for her letters, particularly her letters from Turkey, as wife to the British ambassador, which have been described by Billie Melman as “the very first example of a secular work by a woman about the Muslim Orien

She let her children have vaccinations in Constantinople as early as in 1718, and in 1721 in England, source Helsingin Sanomat April 6, 2016