Sir Stephen Powell, of Howelton

Sir Stephen Powell, who was a brother of Captain Nathaniel Powell, had a son, William Powell, who came to America as a young man in 1620; this William married in this country and had children, among them a Thomas. William died and his children were scattered among friends.

From https://www.ancestry.com/boards/surnames.powell/3442.3457/mb.ashx

(Compiler) Charles S. Powell also states that in 1626, Thomas Powell (the elder brother of Captain Nathaniel Powell), then living in England, petitioned the Government in regard to his estate. They stated that William Powell, who had gotten possession of all of Nathaniel Powell's estate in VA, was no relative of Nathaniel Powell. How the matter was decided there is no record, but in 1653, George Powell, Richard Powell and Mary Powell, supposed to have been the niece and nephews of Nathaniel Powell, made petition for the property, which would indicate that Nathaniel Powell and William Powell left no lineal descendants in VA or elsewhere" (p. 10).