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  • Brevet Brig. General Richard Erskine Holcomb (USA) (1824 - 1863)
    Son of Thomas Holcomb (1779–1865) and Clarinda Pettibone (1781–1855). Richard Holcomb was an explorer of South America who learned to speak both French and Spanish and wrote articles about South Ameri...
  • George Escol Sellers (1808 - 1899)
    George Escol Sellers was an American businessman, mechanical engineer, and inventor. He is associated with designing railroad locomotives and related equipment. He was the target of a confusing name ...
  • Coleman Sellers II (1827 - 1907)
    Coleman Sellers Jr. was a prominent American engineer, chief engineer of William Sellers & Co., professor of mechanics at the Franklin Institute, professor of engineering practice at Stevens Institut...
  • Ralph Budd (1879 - 1962)
    Budd (August 20, 1879 – February 2, 1962) was an American railroad executive.Early lifeRalph was born on a farm near Waterloo, Iowa on August 20, 1879. After graduating at nineteen from Des Moines' Hig...
  • John Lloyd Stephens (1805 - 1852)
    Lloyd Stephens (November 28, 1805 – October 13, 1852) was an American explorer, writer, and diplomat. Stephens was a pivotal figure in the rediscovery of Maya civilization throughout Middle America and...

The Panama Canal Railway is a railway line that runs parallel to the Panama Canal, linking the Atlantic Ocean to the Pacific Ocean in Central America. The route stretches 47.6 miles (76.6 km) across the Isthmus of Panama from Colón (Atlantic) to Balboa (Pacific, near Panama City). It is operated by Panama Canal Railway Company (reporting mark: PCRC), which is jointly owned by Kansas City Southern and Mi-Jack Products.[

The Panama Canal Railway currently provides both freight and passenger service.

The infrastructure of this railroad (formerly named the Panama Railway or Panama Rail Road) was of vital importance for the construction of the Panama Canal over a parallel route half a century later. The principal incentive for the building of the rail line was the vast increase in traffic to California owing to the 1849 California Gold Rush. Construction on the Panama Railroad began in 1850 and the first revenue train ran over the full length on January 28, 1855. Referred to as an inter-oceanic railroad when it opened, it was later also described by some as representing a "transcontinental" railroad, despite only transversing the narrow isthmus connecting the North and South American continents.