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Debbie Bell's Geni Profile

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Deborah Kaye Bell (Allen)

Birthdate:
Birthplace: Old St. Joseph Hospital, Joliet, IL, United States
Immediate Family:

Daughter of Hugh Albert Allen, Jr. and Joyce Marie Sebring
Wife of Private
Mother of Private and Dawnna Marie Mullen
Sister of Private User and Private
Half sister of Private User; Private and Private

Last Updated:
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Immediate Family

About Debbie Bell

I've been married 40 yrs have 2 wonderful children, 2 wonderful step children, 11 Grandchildren, and 9 Great grandchildren.

I got started researching my family in the 1980's over a rumor that we are related to Queen Victoria. That rumor was handed down from the Baer side and after researching I finally found that the rumors were true and my grandmother Arivella Mae Baer, is the Queen's 11th cousin 5x removed.

Arivella married Hugh Allen Sr and had 5 kids and turns out the Allen side is also related to the Queen Victoria. Hugh Albert ALLEN, Jr. is Queen Victoria of the United Kingdom's 12th cousin twice removed.

I don't know why but I like the idea that somewhere in my history was a knight, King, Queen or someone of honor. I know not all of the legends are honorable or true, but searching through the ashes of yesterday is a passion that has grown exponentially in my heart as I've gotten older. Hoping to find you as my cousin...

Happy researching everyone.


Ftdna kit #69425

Haplogroup: U5a2c4

HVR1 Mutations: A16129G, T16187C, C16189T, C16192T, T16223C, G16230A, C16256T, C16270T, T16278C, C16311T, C16519T, G16526A

HVR2 Mutations: C146T, C152T, C195T, A247G, A493G, 522.1A, 522.2C, 315.1C


Gedmatch T857316
Gedcom 8884638


Positive result. Pathogenic variant identified in MSH6.
Variant of Uncertain Significance identified in BRCA1.
Previous analysis performed at a different laboratory reportedly identified a variant in MSH6, p.Q1048*, currently known asc.3142C>T (p.Gln1048*), in this individual’s family member. This variant is detected in this individual and is classified as a Pathogenic variant at Invitae.

  • * The MSH6 gene is associated with autosomal dominant Lynch syndrome (also called hereditary nonpolyposis colorectal cancer syndrome, or HNPCC) (MedGen UID: 318886) and autosomal recessive constitutional mismatch repair deficiency syndrome (CMMR-D) (MedGen UID: 78553).
    • This result is consistent with a predisposition to, or diagnosis of, autosomal dominant MSH6-related conditions.
    • Lynch syndrome is characterized by an increased risk of colorectal cancer as well as cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, and brain (PMID: 8550246, 20533284). The estimated lifetime risk of endometrial cancer in women with a Pathogenic MSH6 variant is 16-26% (PMID: 21642682, 20028993) with one study reporting up to 71% (PMID: 15236168). Other lifetime cancer risks include up to 20% for colorectal cancer, up to 13% of gastric cancer, and up to 8% of ovarian cancer (PMID: 23091106, 15236168, 22619739, 20028993, 25070057). Estimated lifetime risks for men include up to 44% risk of colon cancer, up to 30% risk of prostate cancer, and up to 13% risk of gastric cancer (PMID: 20028993, 25070057, 22619739, 23530095). Risks for other types of cancers may also be elevated (PMID: 19861671, 25070057, 23408351, 15740628, 22476430, 22883484). Clinical management guidelines for Lynch syndrome can be found at www.nccn.org.
    • Close relatives (children, siblings, and each parent) have up to a 50% chance of being a carrier of this variant. More distant relatives may also be carriers. Carriers are at increased risk of developing autosomal dominant MSH6-related conditions and may have reproductive risks related to autosomal recessive MSH6-related conditions as well. Testing for this variant is available.
    • Previous analysis performed at a different laboratory reportedly identified a variant in BRCA1,c.3383T>C (p.Leu1128Pro), in this individual. This variant is detected in this individual and is classified as a Variant of Uncertain Significance at Invitae.
    • The BRCA1 gene is associated with autosomal dominant hereditary breast and ovarian cancer (HBOC) syndrome (MedGen UID: 151793). • The clinical significance of this variant is uncertain at this time. Until this uncertainty can be resolved, caution should be exercised before using this result to inform clinical management decisions