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Mississippi County, Missouri

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Please add profiles of those who were born, lived or died in Mississippi County, Missouri.

Official Website

The county was officially organized on February 14, 1845, and was named after the Mississippi River. It is located in what was formerly known as "Tywappity Bottom," a vast floodplain area bordered by the Scott County Hills on the north, St. James Bayou on the south, the Mississippi River on the east, and Little River on the west.

Mississippi County has borders across the river with four Kentucky counties, but it has no direct highway connection between any of them due to the mile-wide barrier of the river in this area.

Adjacent Counties

Cities, Towns & Communities

  • Alfalfa Center
  • Anniston
  • Bertrand
  • Bird's Point
  • Buckeye
  • Catalpa
  • Charleston (County Seat)
  • Deventer
  • Dogwood
  • Dorena
  • East Prairie
  • Henson
  • Miner (part)
  • Pinhook
  • Pulltight
  • Samos
  • Texas Bend
  • Whiting
  • Wilson City
  • Wolf Island
  • Wyatt



Genealogy Trails


Nat'l Reg. of Hist. Places