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People who died from Arteriosclerosis/Atherosclerosis

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Arteriosclerosis & Atherosclerosis

Arteriosclerosis & Atherosclerosis are often interchanged but are different.

  • Arteriosclerosis is the thickening, hardening and loss of elasticity of the walls of arteries. Unlike atherosclerosis, arteriosclerosis is a sclerosis that only affects small arteries and arterioles, which carry important nutrients and blood to the body’s organs.This process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of arteriosclerosis caused by the buildup of fatty plaques, cholesterol, and some other substances in and on the artery walls.
  • Atherosclerosis is the narrowing of arteries from a build up of plaque, usually made up of cholesterol, fatty substances, cellular waste products, calcium and fibrin, inside the arteries. This affects large and medium-sized arteries; however, its positioning varies person to person. These plaques can burst, triggering a blood clot. Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body. Atherosclerosis may be preventable and is treatable.

Types and pathology of arteriosclerosis Despite being used interchangeably arteriosclerosis is described under three headings – atherosclerosis, Moenckeberg medial calcific sclerosis and arteriolosclerosis. These lesions have three common features including stiffening of arterial vessels, thickening of the arterial wall and degenerative nature of the disease.

  • Moenckeberg arteriosclerosis - The lesions of arteriosclerosis begin as the intima (innermost layer of blood vessel wall) of the arterial wall start to fill up with the deposition of cellular wastes. As these start to mature, they can take different forms of arteriosclerosis. All are linked through common features such as the stiffening of arterial vessels, thickening of arterial walls and degenerative nature of the disease.
  • Monckeberg's arteriosclerosis or medial calcific sclerosis is seen mostly in the elderly, commonly in arteries of the extremities.
  • Hyperplastic: Hyperplastic arteriosclerosis refers to the type of arteriosclerosis that affects the lumen.
  • Hyaline type: Hyaline arteriosclerosis, also referred to as arterial hyalinosis and arteriolar hyalinosis, refers to lesions that are caused by the deposition of homogenous pink hyaline.


  • In 2008, the US had an estimate of 16 million atherosclerotic heart disease and 5.8 million strokes. Cardiovascular diseases that were caused by arteriosclerosis also caused almost 812,000 deaths in 2008, more than any other cause, including cancer. About 1.2 million Americans are predicted to have a heart attack each year.

History of arteriosclerosis

  • The name arteriosclerosis is derived from the Greek words meaning “hardening of the arteries.” Arteriosclerosis is a phenomenon that may have existed since ancient times even in Egypt. It was not until the 20th Century however that the word and its clinical implications became known.
  • It was in 1575 that Fallopius wrote of a condition where arteries degenerated into bones. The anatomists of that time noted these ossified arteries or arteries that had hardened into bone like structures.
  • Johann Friedrich Crell, in 1740 said that this hardening was not due to ossification of turning into bone but due to pus.
  • von Haller in 1755 found that these lesions that Crell thought were pus were actually something else. He named them atheroma that in Greek meant a space filled with gruel like matter.
  • The term arteriosclerosis was first used by Jean Fréderic Martin Lobstein while he analyzed the composition of calcified arterial lesions.
  • George Johnson described in his review on Bright disease in 1868 the noncalcified, nonatheromatous stiffening of small vessels. Gull and Sutton thereafter described arterio-capillary fibrosis that went on to be called arteriosclerosis.

People who died of Arteriosclerosis:

Ranker - Famous People Who Died of Arteriosclerosis (28 listed)

Further Reading:

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