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Skin Cancer Skin cancers -- including melanoma, basal cell carcinoma, and squamous cell carcinoma -- often start as changes to your skin. They can be new growths or precancerous lesions -- changes that are not cancer but could become cancer over time. An estimated 40% to 50% of fair-skinned people who live to be 65 will develop at least one skin cancer. Learn to spot the early warning signs. Sk...