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From http://kykinfolk.com/hopkins/
Hopkins County, the forty-ninth in order of formation, is located in western Kentucky. It has an area of 552 square miles. The county was created on May 1, 1807 from a portion of Henderson County and was named for Gen. Samuel Hopkins, a Revolutionary War veteran and early settler of the region. The county seat is Madisonville.
Some of the early settlers were veterans of the Revolutionary War who received land grants from Virginia in the area southwest of the Green River. Among these was Frederick Wilhelm, Baron Von Steuben, the Prussian general who had instructed the Revolutionary army at Valley Forge in the winter of 1776-77. According to tradition, the baron was wounded during an Indian attack while on his first visit and subsequently quit-claimed his property. On his grant of several thousand acres in the northwest part of the county, a salt spring came to be known as Steuben's Lick. By the 1880s, the community there was called Manitou.
On January 3, 1829, Ashbyburg in the northeastern part of the county was incorporated. Located on the Green River, it thrived as a steamboat landing during the nineteenth century. Other antebellum communities included Nebo, northwest of Madisonville, and Charleston, named after "Free Charles," a black freedman who operated a tavern in the southwest part of the county.
(first arrivers to the county)