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The University of Santo Tomas (also known as UST and officially as the Pontifical and Royal University of Santo Tomas, Manila) is a private, Catholic research university in Manila, Philippines. Founded on April 28, 1611, by Spanish friar Miguel de Benavides, third Archbishop of Manila, it has the oldest extant university charter in the Philippines and in Asia, and is one of the world's largest Catholic universities in terms of enrollment found on one campus. It is the main campus of the University of Santo Tomas System that is run by the Order of Preachers.